Table 1.

Summary of the presented cases.

Patient	1	2	3	4
Gender	Female	Male	Male	Male
Age	59	48	50	53
Smoking	Never	Never	60 py	5 py
Alcohol	Never	Occasionally	Regularly	Occasionally
Oral hygiene	Sufficient	Sufficient	Worse	Moderate
Tumor localization	36	37	46	32
Radiologic signs of periodontal disease	Yes	Yes	Yes	Yes
Probing depths	5 mm	2 mm	7 mm	5 mm
TNM classification	pT2 pN2b pMx G2 R0	pT4 pN0 pM0 G2 R1	pT4a pN2b pM0 G2 pR0	pT4a pN2c pM0 G3 R2
Bleeding upon probing	Yes	No	Yes	Yes
Periodontal marker bacteria	Red complex	Orange and green complex	Orange and orange-associated complex	Not identified
HPV status (p16)	Negative	Negative	Negative	Positive