FIG. 6.

Bone tissue cross-sections at 4 and 8 weeks postsurgery and stained with Paragon for connective tissue (violet) and alizarin red for mineralized bone tissue (red), showing very little bone formation and significant connective tissue in the defect; regeneration and bone growth infiltrating the scaffold (black) in the scaffold and wrap groups and a robust regeneration response are seen in the autograft treatment. Resorption of the collagen membrane is seen from 4 (intact wrap) to 8 weeks (resorbed wrap) in the wrap group; periosteal remodeling of the ulna (labeled P) is also observed in all groups, and cortical-like bone fronts (labeled C) were observed in the wrap and autograft groups.