Table 1.
Area Measurements from Histomorphometric Analysis of Bone Regeneration in the Defect, Scaffold, Wrap, and Autograft Groups at the Defect Interfaces After 4 and 8 Weeks In Vivo
| |
Defect |
Scaffold |
Wrap |
Autograft |
||||
|---|---|---|---|---|---|---|---|---|
| 4 week | 8 week | 4 week | 8 week | 4 week | 8 week | 4 week | 8 week | |
| Bone/total tissue (%) | 21.8±6.8 | 15.7±7.0 | 12.3±2.5 | 32.5±7.4a | 25.6±7.8 | 26.0±5.5 | 77.0±6.5b | 63.0±7.8b |
| Fibrous/total tissue (%) | 71.0±6.1b | 73.0±7.5b | 49.2±1.5 | 37.8±4.0a | 34.6±3.9c | 33.3±1.7 | 22.4±6.1c | 34.7±7.1 |
| New bone area (mm2) | 7.9±1.6 | 5.1±1.1 | 4.1±0.3 | 12.7±2.0a,d | 10.1±1.5c | 13.6±1.2d | 19.7±2.0b | 22.5±1.2b |
| Periosteal remodeling of the ulna (%) | 56±12 | 33±5 | 32±5 | 97±17a,d | 81±12c | 104±13d | 45±6 | 72±8 |
a
A significant increase from 4 to 8 weeks.
b
Significant differences from all other groups.
c
Significant differences from the scaffold group.
d
Significant differences from the defect group.