Table 2.
Hybridomas C1P2 and P20P1 react with different antigens and use different TCRs (modified from Deshmukh et al., 2011)
| Hybridoma | Immunogen | Reactivity | Vα | Vβ |
|---|---|---|---|---|
| C1P2 | SmD | SmD, aSmD79e93, bP20 | TRAV6D-7*04; TRAJ43*01 | TRBV13-1*02; TRBD1*01; TRBJ1-1*01 |
| P20P1 | P20 | SmD, SmD79e93, P20, cP11, dP17 | TRAV12D-2*02; TRAJ16*01 | TRBV13-3*01; TRBD2*01; TRBJ2-5*01 |
a
SmD79–93 LLVDVEPKVKSKKRE SmD aa79-aa93 (Homo sapiens)
b
P20 LD I D IDPKVKVATLS Galactoside ABC transporter aa145-aa159 (V. cholera)
c
P11 KNLD I DPKLQEYLGK La-related protein 1 aa926-aa940 (Homo sapien)
d
P17 EI VDLDPKLKQ I NL I TcmP methyltransferase aa215-aa229 (S. agalactiae)