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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: Behav Brain Res. 2012 Dec 27;242:17–24. doi: 10.1016/j.bbr.2012.12.032

Figure 2.

Figure 2

Spatial learning. Overall all adults had a shorter path length than aged mice, but aged mice treated with minocycline showed a significantly shorter path to the platform compared to aged controls on day 2 (A). Minocycline treatment had no effect on swim speed in aged mice, but increased swim speed in adult mice on day 1 (B). During the probe trial, adult mice crossed the original location of the platform more often than aged mice, but no effect of minocycline treatment was observed (C). * indicates a significant difference from age-matched control group. + indicates a significant difference from treatment-matched adult mice. Bars represent means ± SEMs.