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. Author manuscript; available in PMC: 2013 Jul 29.
Published in final edited form as: Exp Cell Res. 2011 Apr 2;317(11):1548–1566. doi: 10.1016/j.yexcr.2011.03.012

Table 1. Downregulated gene expression in mtDNA-depleted human skin fibroblasts.

Gene Name Gene Symbol Probe ID Fold Change p-value
Rho0/HSF+
Cytochrome b5 reductase 2 (CYB5R2), mRNA CYB5R2 2966 0.14 7.44E-05
Cytochrome b-c1 complex subunit 3)(Complex III subunit 3) CYTB 8924 0.00081 6.00E-07
Fibroblast growth factor 13 (FGF13), transcript variant 1 FGF13 17893 0.1 1.58E-05
Hepatocyte growth factor (HGF), transcript variant 2 HGF 1587 0.19 0.0004288
Insulin-like growth factor binding protein 4 (IGFBP4) IGFBP4 40120 0.4 0.0025358
Insulin-like growth factor binding protein 6 (IGFBP6) IGFBP6 7912 0.29 0.0003373
IGF-like family member 2 (IGFL2), transcript variant 1 IGFL2 7158 0.29 0.0018106
Inhibitor of kappa B, kinase epsilon (IKBKE) IKBKE 16178 0.41 7.12E-05
Interleukin 17B (IL17B) IL17B 16507 0.29 0.0008358
Interleukin 18 (interferon-gamma-inducing factor) (IL18) IL18 914 0.048 0.0011637
Interleukin 19 (IL19), transcript variant 1 IL19 12452 0.19 0.001338
Interleukin 1 receptor, type I (IL1R1) IL1R1 31100 0.33 0.0006962
Interleukin 1 receptor accessory protein-like 2 (IL1RAPL2) IL1RAPL2 8613 0.28 0.004756
Interleukin 21 receptor (IL21R), transcript variant 2 IL21R 31421 0.043 2.46E-05
Interleukin 24 (IL24), transcript variant 1 IL24 21732 0.22 0.0001206
Interleukin 28B (IL28) (interferon, lambda 3) IL28B 25800 0.33 0.0023302
Interleukin 31 receptor A (IL31RA) IL31RA 33280 0.18 0.0009293
Interleukin 6 (interferon, beta 2) (IL6) IL6 9255 0.43 0.0040936
Mitogen-activated protein kinase kinase kinase 8 (MAP3K8) MAP3K8 8124 0.29 0.004285
Metallothionein 1M (MT1M) MT1M 29528 0.046 4.60E-05
Nuclear factor of activated T-cells, cytoplasmic 1 (NF-ATC1) NFATC1 22496 0.12 6.95E-05
Plasminogen activator, urokinase (PLAU) PLAU 1130 0.057 4.40E-05
Peroxisome proliferator-activated receptor gamma, coactivator 1 PPARGC1A 7742 0.17 0.0003335
Protein kinase C, theta (PRKCQ) PRKCQ 33583 0.32 0.0011877
Prostaglandin E synthase (PTGES) PTGES 33403 0.39 0.0007839
Ribosomal protein S6 kinase-like 1 (RPS6KL1) RPS6KL1 14792 0.25 0.0035587
Transforming growth factor, beta-induced, 68kDa (TGFBI) TGFBI 22104 0.43 0.0049484
Tumor necrosis factor, alpha-induced protein 6 (TNFAIP6) TNFAIP6 31876 0.066 6.00E-06
Tumor necrosis factor receptor superfamily, member 10a (TNFRSF10A) TNFRSF10A 15317 0.41 0.0011807
Tumor necrosis factor receptor superfamily, member 19 (TNFRSF19) TNFRSF19 28863 0.21 0.0010152