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The boxplot of the 12 signatures. Total 12 signatures showed differential activities between cholangiocarcinoma (CAC) and hepatocellular carcinoma (HCC). (A) 9 signatures were up-regulated in CAC, and (B) 3 showed down regulation. The P-values of t-test of the 12 signatures were all smaller than 0.01. CHC is the mixed type of combined HCC and CAC
