Table 3.
Dose ※ (mg/kg) | Tumor weight (g) | Inhibitory rate *(%) | |
---|---|---|---|
CTX | 20.00 | 0.463 ± 0.180 | 68.3 ± 12.2 |
PTL | 3.25 | 0.935 ± 0.160 | 36.2 ± 10.9 |
2.30 | 0.995 ± 0.131 | 32.1 ± 8.9 | |
0.85 | 1.236 ± 0.132 | 15.6 ± 9.0 | |
Negative control (0.9%NaCl) | - | 1.465 ± 0.122 | - |
The anti-tumoral effect was determined by examining the tumor weight and calculating the inhibition rate as described below. The value of P (p<0.005) was calculated according to the tumor weight at every experiment group.
※Each dose was tested in 12 mice every other day for 10 days;
*Inhibitory rate = [(tumor weight of control mice-tumor weight of experimental mice)/tumor weight of control mice]x100%.