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. 2009 Dec 4;69(2):120–130. doi: 10.1159/000264449

Table 3.

Empirical sizes and powers of various tests with nominal significance level α = 0.05 for simulated data based on the LD patterns in gene IL21R with 27 SNPs

n OR Sco SSU SSUw UminP Sum Test combination
Test selection
MinP Fisher TPM
500 1.0 0.039 0.042 0.044 0.055 0.050 0.053 0.040 0.041 0.068
1.2 0.123 0.202 0.208 0.182 0.164 0.180 0.197 0.208 0.233
1.3 0.205 0.402 0.402 0.417 0.304 0.413 0.432 0.419 0.453
1.4 0.369 0.594 0.589 0.652 0.432 0.650 0.644 0.618 0.682
1.5 0.526 0.737 0.740 0.829 0.527 0.829 0.800 0.779 0.831
1.6 0.691 0.828 0.836 0.909 0.607 0.911 0.904 0.875 0.918

1,000 1.0 0.042 0.044 0.043 0.049 0.034 0.046 0.047 0.049 0.066
1.2 0.214 0.390 0.391 0.411 0.286 0.404 0.403 0.397 0.445
1.3 0.441 0.679 0.670 0.730 0.499 0.729 0.734 0.708 0.760
1.4 0.726 0.826 0.826 0.917 0.604 0.919 0.892 0.873 0.922
1.5 0.905 0.912 0.920 0.974 0.699 0.976 0.970 0.971 0.975
1.6 0.973 0.960 0.966 0.991 0.767 0.993 0.993 0.991 0.989