Table 2.

Histological Scoring Evaluation

Sample	HA-FIB			HA-FIB-B3.75			HA-FIB-B5
Time point	1 week	3 week	6 week	1 week	3 week	6 week	1 week	3 week	6 week
Scoring categories
1. Intensity	0.82±0.98	1.82±0.87	2.70±0.48	0.67±0.78	1.82±0.60	3.00±0.00	1.00±1.00	1.91±0.54	2.64±0.50
2. Density	0.55±0.69	1.36±0.50	2.10±0.57	1.00±0.95	1.64±0.47	2.27±0.65	1.00±0.89	1.91±0.83	2.45±0.69
3. Morphology	1.27±1.35	1.82±0.40	2.50±0.53	1.08±1.00	1.73±0.67	2.91±0.30	1.36±1.29	2.00±0.63	2.55±0.69
4. Uniformity	0.55±0.69	1.64±0.50	2.20±0.63	0.92±1.00	1.64±0.50	2.55±0.69	0.91±0.94	1.36±0.50	2.00±1.00
5. Calcifications	3.00±0.00	3.00±0.00	2.40±0.52	3.00±0.00	3.00±0.00	2.91±0.30	3.00±0.00	3.00±0.00	3.00±0.00
6. Vascularization	2.67±0.71	1.22±0.67	1.38±0.74	3.00±0.00	1.78±0.67a	2.78±0.44b	2.78±0.44	1.89±0.60a	2.67±0.50b
Final score	8.85±2.06	10.86±1.39	13.28±1.43	9.76±1.87	11.6±1.32	16.41±1.13c	10.05±2.13	12.07±1.41a	15.3±1.57b

Statistical differences evaluated between the scaffolds with and without bevacizumab at each time point.

^ap<0.05.

^bp<0.01.

^cp<0.001.