Table 4.

Follow-up results of neuropsychological findings among dementia subtypes including confirmed AD

	Confirmed AD (n=206)	DLB (n=11)	Insufficient AD (n=11)	Vascular D. (n=10)	FTLD (n=7)	HS (n=6)	p value*
Δ MMSE	−4.80±4.94	−4.18±5.19	−3.09±4.18	−2.90±3.28	−7.43±7.04	−6.50±6.28	0.542
Δ Logical Memory IA-Immediate	−1.68±2.67	−0.71±5.12	−0.71±1.80	−0.33±4.36	−1.00±0.00	−3.00±2.45	0.691
Δ Digit Span Forward	−0.73±1.55	0.17±2.14	0.43±0.98†	0.10±0.32†	−1.50±0.71	−1.20±1.26	0.044
Δ Digit Span Backward	−0.81±1.24	0.17±2.14	−0.57±0.98	−0.10±0.99†	−1.50±0.71	−0.25±0.50	0.228
Δ Category Fluency
Δ Animals	−3.07±3.50	−3.13±3.72	−4.00±4.90	−1.40±2.67	−4.00±0.00	−2.25±2.50	0.718
Δ Vegetables	−2.23±2.61	−2.75±2.49	−3.33±3.01	−1.70±2.79	−0.50±4.95	−2.50±0.58	0.729
Δ Trail Making Test (sec)
Δ Part A	21.81±34.09	36.83±18.16	33.17±42.05	13.56±39.78	53	56.75±58.77
Δ Part B	0.00±0.00	0.00±0.00	0.00±0.00	0.00±0.00	0	0
Δ WAIS-Digit Symbol	0.00±0.00	0.00±0.00	0.00±0.00	0.00±0.00		0.00±0.00
Δ Logical Memory IIA-Delayed	−0.63±2.44	−0.57±2.99	2.00±3.83†	−1.89±3.06	0	−0.50±1.29	0.183
Δ BNT	−4.52±5.01	−2.75±3.58	−0.67±1.86†	−1.60±5.27†	−1.67±8.33	−4.50±5.69	0.048

Values are presented as mean±standard deviation, and differences between the last and first examinations.

^*Comparisons among dementia subtypes such as confirmed AD, DLB, insufficient AD, vascular disease, FTLD, and HS by analysis of covariances.

^†Significant difference after multiple comparisons by Scheffee method, compared to confirmed AD.

Age was adjusted for the analyses.

AD, Alzheimer’s Disesae; DLB, dementia with Lewy body; FTLD, fontotemporal lobar degeneration; HS, hippocampal sclerosis; MMSE, mini-mental state examination; WAIS, Wechsler Adult Intelligence Scale; BNT, Boston naming test.