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. Author manuscript; available in PMC: 2013 Jul 29.
Published in final edited form as: Bioorg Med Chem. 2009 Dec 6;18(2):640–649. doi: 10.1016/j.bmc.2009.12.002

Fig. 3.

Fig. 3

Carboxylic acid esters inhibit specific [3H]DA (top panel) and [3H]5-HT (bottom panel) uptake into rat striatal and hippocampal synaptosomes, respectively. GBR 12909 and fluoxetine were used as a positive controls for [3H]DA and [3H]5-HT uptake assays, respectively . Nonspecific uptake was determined in the presence of nomifensine (10 μM) and fluoxetine (10 μM), respectively. Data are presented as mean ± SEM as a percent control (Control [3H]DA uptake values = 34.3 ± 1.53 pmol/min/mg; Control [3H]5-HT uptake values = 2.47 ± 0.15 pmol/min/mg).