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. 2012 Jul;2(3):87–91. doi: 10.1177/1941874412446199

Table 3.

Stroke Subtypes, Severity, Pathogen, Intervention, and Outcomes

Patient # Presenting Stroke Subtype
Initial NIHSS Diagnosed IE at Stroke Presentation Pathogen Intervention Follow-Up Imaging Outcome (mRS)
Ischemia ICH SAH
 1a X 15 No S viridans IV-tPA HT (ICH) 5
 2 X X 4 Suspected S viridans None Expected evolution 6
 3a X 16 Suspected E faecalis None Expected evolution 4
 4 X 13 Yes P aeruginosa None Expected evolution 6
 5a X 14 No Coag-neg Staph IA-tPA, Merci HT (ICH), SDH 6
 6 X 1 Suspected None identified None Not done 0
 7 X 2 No S lugdunensis None Not done 1
 8 X X No MSSA None New ischemia, HT (ICH + IVH) 5
 9a X 8 No E faecalis IV-tPA ICH, SAH 6
10a X 14 No E Faecalis IV-tPA, Merci HT (ICH + IVH), SAH 6
11 X X 14 No None identified None New ischemia 6
12 X X 20 Yes None identified None Expected evolution 6
13b X X Yes Staphylococcus IA-tPA, angioplasty Expected evolution 6
14 X 19 No Enterococcus None Expected evolution 4
15 X 1 Yes S milleri None SDH 1
16 X X No MSSA None Expected evolution 6
17 X 14 Suspected None identified None New ischemia, HT 6
18 X 9 No MSSA None Expected evolution 4

Abbreviations: Coag-neg Staph, coagulase-negative Staphylococcus; E faecalis, Enterococcus faecalis; HT, hemorrhagic transformation; IA-tPA, intra-arterial tissue plasminogen activator; ICH, intracranial hemorrhage; IV-tPA, intravenous tissue plasminogen activator; IVH, intraventricular hemorrhage; mRS, modified Rankin Scale; MSSA, methicillin-sensitive Staphylococcus aureus; NIHSS, National Institute of Health Stroke Scale; P aeruginosa, Pseudomonas aeruginosa; S lugdunensis, Staphylococcus lugdunensis; S milleri, Streptococcus milleri; S viridans, Streptococcus viridans; SAH, subarachnoid hemorrhage; SDH, subdural hematoma.

a Presented within 6 hours of stroke symptom onset.

b This patient had known endocarditis and a minor SAH on presentation, but after discussion with the family and in the setting of a disabling left middle cerebral artery stroke, he received IA-tPA and angioplasty. This restored blood flow without worsening SAH on follow-up imaging, but he never regained consciousness and died 3 days later.