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. 2013 Jul 1;123(8):3211–3230. doi: 10.1172/JCI65521

Figure 9. APEX1 regulates tumor metastasis through Jagged1 in a mouse model.

Figure 9

The indicated DLD1-RFP (A) and SW480-RFP (B) cells were injected into the abdominal cavity of BALB/c mice (n = 6), and colon cancer metastasis to the lung was measured by fluorescence expression. Shown are representative fluorescence images at 5 (DLD1) and 8 (SW480) weeks after injection and histological analyses showing RFP fluorescence of lung tissue sections. Scale bars: 40 μm (A and B).