Table 1. Comparison of the ¹H-¹³C-chemical shifts pairs in C8-dG-PhIP in the nucleoside adduct in DMSO versus the 11mer duplex adduct in aqueous buffer.

	Nucleosidea	11mer duplex (major)	11mer duplex (minor)
N-CH3	3.65–28.11	3.04–29.47	3.74–31.38
H7	8.01–113.42	7.09–114.73	7.99–ndb
H5	8.41–139.48	7.04–138.07	8.40–138.31
H6′/H2′	7.76–126.79	7.29–130.40	7.84–ndb
H5′/H3′	7.49–128.97	7.06–128.21	7.81–129.81
H4’	7.38–127.34	7.29–131.28	7.29–131.28

^aValues reported by Frandsen et al. (21).

^bNot detected.