Table 1. Characteristics of NMSC Cohort According to LLE Category.
| LLE Subgroups, %a |
||||
|---|---|---|---|---|
| Characteristic | Overall Cohort, % (N = 1360) |
Yes (n = 332) |
No (n = 536) |
P Value |
| Patient | ||||
| Age, median (IQR), y | 69.0 (55.0-78.0) | 79.0 (69.0-86.0) | 63.0 (52.0-74.0) | <.001 |
| Sex, male | 72.7 | 78.0 | 72.6 | .09 |
| Charlson Comorbidity Index,13 median (IQR) | 1.0 (0.0-3.0) | 6.0 (3.0-7.0) | 0.0 (0.0-1.0) | <.001 |
| Fitzpatrick skin type 1 or 218 | 39.0 | 39.8 | 38.8 | .85 |
| History of prior NMSC | 51.1 | 55.7 | 52.4 | .38 |
| No. of NMSC at baseline, median (IQR) | 1.0 (1.0-1.0) | 1.0 (1.0-1.0) | 1.0 (1.0-1.0) | .68 |
| History of HIV | 3.1 | 3.0 | 3.7 | .71 |
| History of organ transplantation | 2.7 | 4.5 | 1.1 | .003 |
| Annual income, <$30 000 | 50.7 | 63.1 | 45.1 | <.001 |
| Education, high school or less | 37.1 | 46.5 | 32.6 | <.001 |
| Tumor | n = 1739 | n = 428 | n = 678 | |
| Tumor diameter, mean (IQR), mm | 8.0 (5.0-13.0) | 9.0 (6.0-15.0) | 8.0 (5.0-12.0) | <.001 |
| Tumor on central face | 35.1 | 40.7 | 34.1 | .03 |
| Basal cell carcinoma | 74.6 | 63.1 | 81.3 | <.001 |
| Superficial pathology | 30.7 | 30.8 | 30.2 | .88 |
| High-risk histology,10 | 19.3 | 17.3 | 21.7 | .09 |
| Bothers patient frequently | 21.7 | 27.5 | 18.8 | .03 |
| Care setting | ||||
| Treated at VAMC | 39.5 | 51.2 | 41.0 | .004 |
| Treated at private hospital | 60.5 | 48.8 | 59.0 | |
| Attending physician performed biopsy | 58.4 | 44.6 | 61.3 | |
| Resident physician performed biopsy | 24.7 | 37.6 | 19.2 | <.001 |
| Nurse practitioner performed biopsy | 16.9 | 17.8 | 19.5 | |
| No. of annual patient visits to dermatology, median (IQR) | 1.6 (0.5-2.8) | 1.9 (0.7-3.1) | 1.7 (0.6-3.0) | .18 |
Abbreviations: HIV, human immunodeficiency virus; IQR, interquartile range; LLE, limited life expectancy; NMSC, nonmelanoma skin cancer; VAMC, Veterans Affairs Medical Center.
a
The sum of the number of patients in LLE plus non-LLE is smaller than the total cohort because we had 492 missing data points for patient-reported Charlson index, which is part of the definition of LLE.