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. Author manuscript; available in PMC: 2014 Aug 6.
Published in final edited form as: Neuroscience. 2013 Apr 6;244:1–15. doi: 10.1016/j.neuroscience.2013.03.058

Figure 7.

Figure 7

Correlation of measures of neurogenesis and disinhibition in the open field conflict and locomotor behavior. (Upper panel) Correlations between DCX-IR measures of neurogenesis and the modified open field conflict for animals sacrificed at PD72 and PD114. For animals sacrificed at PD114, distance from the food pellet (shorter distance means more disinhibition) had a positive correlation with DCX-IR. This effect was similar to what was seen with animals sacrificed at PD72 where more food approaches are negatively correlated with DCX-IR. Both measures show that decreases in neurogenesis correlate with measures of disinhibition. (Lower panel) Correlations between DCX-IR measures of neurogenesis and locomotor behavior 24 hours withdrawal from alcohol for animals sacrificed at PD72 and PD114. Both groups of animals show a decrease in DCX-IR that correlates with a decrease in locomotor activity at 24 hours withdrawal from alcohol. Ethanol and control animals are graphed separately with a linear regression line plotted for all data points