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. Author manuscript; available in PMC: 2013 Jul 29.
Published in final edited form as: Anesthesiology. 2010 Sep;113(3):619–629. doi: 10.1097/ALN.0b013e3181e89ab2

Figure 2. Lung tissue histopathology in TLR4-WT and TLR4-mutant mice following VILI.

Figure 2

Representative photomicrographs of hematoxylin and eosin staining (× 20 objective) of lungs from TLR4-WT (A, B, C) and TLR4-mutant (D, E, F) mice subjected to unventilated and tracheotomized control (CON), low tidal volume ventilation (LTV), and high tidal volume ventilation (HTV). HTV illustrates a marked increase in inflammatory cell infiltration, alveolar septal thickening, and pulmonary edema in the lung in TLR4-WT mice (C) compared to TLR4-mutant mice (F).