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. 2013 Jul 23;10:93. doi: 10.1186/1742-2094-10-93

Table 1.

Effect of NF-κB inhibitors on neuronal survival and release of lactate dehydrogenase

  Neuronal survivala Lactate dehydrogenase releasedb
Control
100.2 ± 3.8
100.1 ± 3.9
Sunitinib
127.7 ± 7.8 **
85.9 ± 2.9 **
Sunitinib + SN50
98.8 ± 6.1 ##
123.9 ± 2.7 ###
Sunitinib + Bay11-7085
83.0 ± 7.9 ###
123.6 ± 2.7 ###
Sunitinib + dicoumarol 110.4 ± 12.6 100.4 ± 5.7 #

aCell survival was measured by MTT assay. Data are mean ± SEM from three experiments.

bCell death was determined by level of released lactate dehydrogenase. Data are mean ± SEM from three experiments.

**P < 0.01 vs control.

#P < 0.05, ##P < 0.01, ###P < 0.001 vs sunitinib alone.

SEM, standard error of the mean.