Table 1.
Neuronal survivala | Lactate dehydrogenase releasedb | |
---|---|---|
Control |
100.2 ± 3.8 |
100.1 ± 3.9 |
Sunitinib |
127.7 ± 7.8 ** |
85.9 ± 2.9 ** |
Sunitinib + SN50 |
98.8 ± 6.1 ## |
123.9 ± 2.7 ### |
Sunitinib + Bay11-7085 |
83.0 ± 7.9 ### |
123.6 ± 2.7 ### |
Sunitinib + dicoumarol | 110.4 ± 12.6 | 100.4 ± 5.7 # |
aCell survival was measured by MTT assay. Data are mean ± SEM from three experiments.
bCell death was determined by level of released lactate dehydrogenase. Data are mean ± SEM from three experiments.
**P < 0.01 vs control.
#P < 0.05, ##P < 0.01, ###P < 0.001 vs sunitinib alone.
SEM, standard error of the mean.