Table 2.
Results of the linear regression analyses as well the Bland-Altman-analyses of the creatinine-based eGFR values (dependent variable) versus the kinetically determined mGFR values (95% confidence intervals in parentheses)
| eGFR Variable | Total mGFR range | mGFR <= 60 (mL/min)/1.73 m2 | mGFR > 60 (mL/min)/1.73 m2 | 60 < mGFR <= 90 (mL/min)/1.73 m2 | mGFR > 90 (mL/min)/1.73 m2 | |
|---|---|---|---|---|---|---|
|
CKD-EPI |
Intercept |
14.7 (6.9 – 22.4) |
−9.8 (-29.5 – 9.9) |
34.7 (20.5 – 48.9) |
1.7 (-44.8 – 48.2) |
64.9 (41.3 – 88.2) |
| Slope |
0.67 (0.59 – 0.75) |
1.13 (0.71 – 1.55) |
0.49 (0.36 – 0.62) |
0.86 (0.25 – 1.47) |
0.24 (0.04 – 0.44) |
|
| R* |
0.78 (0.71 – 0.83) |
0.66 (0.44 – 0.80) |
0.55 (0.42 – 0.66) |
0.47 (0.14 – 0.71) |
0.23 (0.03 – 0.41) |
|
| Bias+ |
14.8 (11.8 – 17.9) |
3.8 (-1.3 – 8.9) |
18.4 (14.8 – 21.9) |
8.6 (3.2 – 14.1) |
21.5 (17.3 – 25.7) |
|
| Limits of agreement |
−24.9 – 54.6 |
−27.9 – 35.6 |
−21.4 – 51.9) |
−20.2 – 37.6 |
−19.3 – 62.2 |
|
| |
|
|
|
|
|
|
| MDRD | Intercept |
14.9 (7.0 – 22.9) |
−6.7 (-24.4 – 11.0) |
34.7 (19.0 – 49.1) |
10.4 (-30.2 – 51.1) |
61.3 (35.4 – 87.2) |
| Slope |
0.64 (0.55 – 0.72) |
1.03 (0.66 – 1.41) |
0.46 (0.32 – 0.60) |
0.72 (0.18 – 1.25) |
0.24 (0.01 – 0.46) |
|
| R |
0.76 (0.69 – 0.82) |
0.67 (0.46 – 0.81) |
0.50 (0.36 – 0.62) |
0.45 (0.11 – 0.69) |
0.21 (0.01 – 0.3) |
|
| Bias |
17.9 (14.7 – 21.1) |
5.2 (0.6 – 9.7) |
22.0 (18.2 – 25.7) |
11.1 (6.3 – 15.9) |
25.4 (20.9 – 29.9) |
|
| Limits of agreement | −23.5 – 59.3 | −23.1 – 33.5 | −19.9 – 63.9 | −14.6 – 36.9 | −18.4 – 69.3 | |
*R, linear correlation coefficient.
+Bias is defined as mean of mGFR minus mean of eGFR.