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. 2013 Jul 29;8(7):e70193. doi: 10.1371/journal.pone.0070193

Table 2. Genotype and allele frequency of CFH rs1061170 by Logistic Regression analysis.

Unadjusted p value Multivariate analysis, adjusted for age, gender, food habits, smoking and comorbidity
Genotype Number (frequency) OR 95% CI p Value OR 95% CI P Value
CFH rs1061170
AMD Controls
TT 20 (.183) 45 (.763) Reference Reference
TC 45 (.413) 8 (.136) 12.65 5.05–31.69 0.0001 1.960 0.393–3.526 0.014
CC 44 (.404) 6 (.101) 16.5 6.05–44.96 0.0001 * * *
Wet AMD Dry AMD
TT 16 (.20) 4 (.138) Reference Reference
TC 33 (.412) 12 (.414) 0.69 0.191–2.471 0.566 1.447 0.897–3.791 0.226
CC 31 (.388) 13 (.448) 0.60 0.167–2.129 0.426 0.400 0.049–3.289 0.394
Allele Number (frequency) OR 95% CI p Value
AMD Controls
T 85 (.39) 98 (.83) Reference
C 133 (.61) 20 (.17) 7.6 4.4–13.3 0.0001 - - -
Wet AMD Dry AMD
T 65 (.41) 20 (.34) Reference
C 95 (.59) 38 (.66) 0.77 0.41–1.43 0.41 - - -
*

The value could not be complied because of the equal frequencies.