Table 2. Genotype and allele frequency of CFH rs1061170 by Logistic Regression analysis.
Unadjusted p value | Multivariate analysis, adjusted for age, gender, food habits, smoking and comorbidity | |||||||
Genotype | Number (frequency) | OR | 95% CI | p Value | OR | 95% CI | P Value | |
CFH rs1061170 | ||||||||
AMD | Controls | |||||||
TT | 20 (.183) | 45 (.763) | Reference | Reference | ||||
TC | 45 (.413) | 8 (.136) | 12.65 | 5.05–31.69 | 0.0001 | 1.960 | 0.393–3.526 | 0.014 |
CC | 44 (.404) | 6 (.101) | 16.5 | 6.05–44.96 | 0.0001 | * | * | * |
Wet AMD | Dry AMD | |||||||
TT | 16 (.20) | 4 (.138) | Reference | Reference | ||||
TC | 33 (.412) | 12 (.414) | 0.69 | 0.191–2.471 | 0.566 | 1.447 | 0.897–3.791 | 0.226 |
CC | 31 (.388) | 13 (.448) | 0.60 | 0.167–2.129 | 0.426 | 0.400 | 0.049–3.289 | 0.394 |
Allele | Number (frequency) | OR | 95% CI | p Value | ||||
AMD | Controls | |||||||
T | 85 (.39) | 98 (.83) | Reference | |||||
C | 133 (.61) | 20 (.17) | 7.6 | 4.4–13.3 | 0.0001 | - | - | - |
Wet AMD | Dry AMD | |||||||
T | 65 (.41) | 20 (.34) | Reference | |||||
C | 95 (.59) | 38 (.66) | 0.77 | 0.41–1.43 | 0.41 | - | - | - |
The value could not be complied because of the equal frequencies.