Table 3. Logistic regression of CFH rs1061170 and AMD stratified by food habits, smoking and comorbidities.
Unadjusted p value | Multivariate analysis, adjusted for age and sex | |||||||
Genotype | Number (frequency) | OR | 95%CI | p-value | OR | 95%CI | p-value | |
CFH rs1061170 | ||||||||
Vegetarian AMD | Non Vegetarian AMD | |||||||
TT | 6 (0.10) | 14 (0.28) | Reference | Reference | ||||
TC | 29 (0.50) | 16 (0.31) | 4.22 | 1.35–13.15 | 0.012 | 0.404 | 0.113–1.445 | 0.164 |
CC | 23 (0.40) | 21 (0.41) | 2.55 | 0.83–7.86 | 0.102 | 2.579 | 0.589–11.29 | 0.209 |
AMD Smokers | AMD Non Smokers | |||||||
TT | 9 (0.19) | 11 (0.18) | Reference | |||||
TC | 22 (0.47) | 23 (0.37) | 1.16 | 0.40–3.36 | 0.772 | 1.00 | 0.271–3.694 | 1.00 |
CC | 16 (0.34) | 28 (0.45) | 0.69 | 0.23–2.04 | 0.512 | 0.412 | 0.70–2.42 | 0.327 |
AMD with Comorbodities | AMD without Comorbodities | |||||||
TT | 11 (0.14) | 9 (0.32) | Reference | Reference | ||||
TC | 36 (0.46) | 8 (0.29) | 3.68 | 1.145–11.83 | 0.028 | 0.083 | 0.08–0.898 | 0.040 |
CC | 32 (0.40) | 11 (0.39) | 2.38 | 0.779–7.265 | 0.127 | 1.836 | 0.462–7.29 | 0.388 |