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. 2013 Jul 29;8(7):e70163. doi: 10.1371/journal.pone.0070163

Figure 7. The effect of Prdx6 siRNA knockdown on Nrf2 protection against tBOOH.

Figure 7

Vehicle or tBHQ treated astrocytes were pretreated with A) non-targeting siRNA (siNT) or B) peroxiredoxin-6 siRNA (siPrdx6) or with either C) a vehicle control (Veh) or D) a peroxiredoxin-6 inhibitor, mercaptosuccinate (MS). tBOOH toxicity curves were performed as indicated. Cell viability was determined by MTS. Statistics were performed using 2-way ANOVA, * indicates p<0.01.