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. 2013 Jul 6;7:57. doi: 10.1186/1752-0509-7-57

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Copyright © 2013 Santra et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Best performers in reconstructing the the MAPK pathway at different levels of signal dependent and independent noises. The performances were evaluated for different levels of signal dependent (β_s, X-axis) and independent (α_b, Y-axis) components of the measurement errors. β_s and α_b were gradually increased from a minimum of 0.1 up to 1 and from 0.01 up to 0.1 respectively. The best performers in terms of maximum average AUROC(p<0.05)and maximum average AUPR(p<0.05) are shown in panels (a) and (b) respectively.