Table 3. Rate of VTE per 100,000 person-years using different definitions of VTE in and around pregnancy (for pregnancies resulting in live or stillbirths).
Time period | VTE definition A1, B2 or C3 | VTE definition A1 or B2 | VTE definition A1 | |||
n | Rate* (95%CI) | n | Rate* (95%CI) | n | Rate* (95%CI) | |
Not pregnant | 2,817 | 61 (58–63) | 2040 | 44 (42–46) | 1480 | 32 (30–33) |
Antepartum | 377 | 240 (217–266) | 268 | 171 (151–192) | 156 | 99 (85–116) |
Trimester 1 | 47 | 95 (71–127) | 41 | 83 (61–113) | 23 | 46 (31–70) |
Trimester 2 | 76 | 148 (118–186) | 49 | 95 (74–126) | 30 | 58 (41–83) |
Trimester 3 | 254 | 450 (398–509) | 178 | 315 (272–365) | 103 | 182 (150–221) |
Around delivery | 76 | 3192 (423–546) | 38 | 1596 (1161–2193) | 34 | 1428 (1020–1998) |
Postpartum | 237 | 481 (423–546) | 187 | 379 (329–438) | 135 | 274 (231–324) |
Early postpartum | 200 | 801 (695–920) | 157 | 629 (537–735) | 177 | 468 (391–561) |
Late postpartum | 37 | 151 (109–208) | 30 | 122 (95–175) | 18 | 73 (46–116) |
Rate per 100,000 person-years.
With women recorded as having a VTE event if they had a diagnosis in either database.
Recorded VTE with supporting anticoagulant prescription, or medical code indicating anticoagulant therapy within 90 days of the event or death within 30 days of the event.
Recorded VTE codes with supporting sign or symptom of VTE within 15 days before or after the date of event.
Recorded VTE with no evidence of signs and symptoms or anticoagulant therapy.