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. 2013 Jul 29;8(7):e70310. doi: 10.1371/journal.pone.0070310

Table 3. Rate of VTE per 100,000 person-years using different definitions of VTE in and around pregnancy (for pregnancies resulting in live or stillbirths).

Time period VTE definition A1, B2 or C3 VTE definition A1 or B2 VTE definition A1
n Rate* (95%CI) n Rate* (95%CI) n Rate* (95%CI)
Not pregnant 2,817 61 (58–63) 2040 44 (42–46) 1480 32 (30–33)
Antepartum 377 240 (217–266) 268 171 (151–192) 156 99 (85–116)
Trimester 1 47 95 (71–127) 41 83 (61–113) 23 46 (31–70)
Trimester 2 76 148 (118–186) 49 95 (74–126) 30 58 (41–83)
Trimester 3 254 450 (398–509) 178 315 (272–365) 103 182 (150–221)
Around delivery 76 3192 (423–546) 38 1596 (1161–2193) 34 1428 (1020–1998)
Postpartum 237 481 (423–546) 187 379 (329–438) 135 274 (231–324)
Early postpartum 200 801 (695–920) 157 629 (537–735) 177 468 (391–561)
Late postpartum 37 151 (109–208) 30 122 (95–175) 18 73 (46–116)
*

Rate per 100,000 person-years.

**

With women recorded as having a VTE event if they had a diagnosis in either database.

1

Recorded VTE with supporting anticoagulant prescription, or medical code indicating anticoagulant therapy within 90 days of the event or death within 30 days of the event.

2

Recorded VTE codes with supporting sign or symptom of VTE within 15 days before or after the date of event.

3

Recorded VTE with no evidence of signs and symptoms or anticoagulant therapy.