Table 5.
Toxicity: patients who suffered at least one single event
| Group A (control group) | Group B (IFN-α) | Group C (IFN-γ) | Group D (IFN-α and IFN-γ) | |
|---|---|---|---|---|
| Patients | 48 | 39 | 35 | 42 |
| Fever | 7 (15) | 14 (35) | 12 (34) | 17 (40) |
| Anorexia | 19 (40) | 21 (60) | 20 (56) | 27 (65) |
| Fatigue | 11 (22) | 16 (40) | 13 (38) | 21 (50) |
| Anemia | ||||
| Grade 1/2 | 19 | 11 | 12 | 10 |
| Grade 3 | 3 | 2 | 4 | 5 |
| Neutropenia | ||||
| Grade 1/2 | 19 | 10 | 19 | 34 (P < 0.001) |
| Grade 3/4 | 4 | 3 | 5 | 7 |
| Thrombocytopenia | ||||
| Grade 1/2 | 6 | 2 | 2 | 4 |
| Grade 3/4 | 5 | 6 | 4 | 3 |
Note: Values are presented as absolute numbers, and percentage in parentheses.
Abbreviations: IFN-α, interferon alpha; IFN-γ, interferon gamma.