Figure 6.

(A and B) 868 TCR-transduced CTLs kill less efficiently when treated with Feraspin R. FATAL assays were performed using (A) CTLs pretreated with various concentrations of Feraspin R for 24 hours at various effector:target (E:T) ratios, and (B) CTLs treated for 24 hours with 1 mg/mL Feraspin R at various concentrations of SLYNTVATL peptide-pulsed T2 cells.

Note: All FATAL assays were incubated overnight and performed in duplicate.

Abbreviations: TCR, T-cell receptor; CTL, cytotoxic T lymphocyte; FATAL, fluorometric assessment of T-lymphocyte antigen-specific lysis; E:T, effector:target.