Table 3.

Multivariate analysis for factors related to overall survival following reirradiation

Factors (in favor of)	p
Primary site (lung)	0.01
Pretreatment KPS (≥60)	0.03
Interval between two courses of WBRT (≥9.5 months)	0.01
SRS (application)	0.57
Extracranial metastasis (in control)	0.86
Number of metastasis in the brain (<5)	0.48
BEDcumulative (≥129.5 Gy)	0.62

KPS Karnofsky performance scale, WBRT whole brain radiotherapy, SRS stereotactic radiosurgery, BED biological effective dose.