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. 2013 Jul 29;8(7):e70073. doi: 10.1371/journal.pone.0070073

Table 1. The influence of clinical factors on neonatal sedation (Infant ADR).

(N = 5) (N = 233)
Infant ADR Asymptomatic P Value
No. days taking codeine 4.8±2.6 2.5±1.6 0.01
Total amount of codeine used (mg/kg) 5.1±2.4 3.2±2.5 0.08
No. times feeding per day 8.5 (7.0–9.0) 9.0 (3.0–13.0) 0.27
Baby GA (weeks) 38.6±1.1 39.1±1.4 0.44
Baby Birth Weight (g) 3392.4±584.4 3403.1±510.12 0.96
No. consecutive hours slept 3.5 (2.5–4.0) 2.5 (1.5–4.5) 0.19
Maternal ADR 0 8% (19/242) 0.67
Formula supplementation 20% (1/5) 17% (39/229) 0.41
Non-Caucasian 100% (5/5) 62% (143/230 0.10

Demographic characteristics of Mothers of sedated infants (Infant ADR) and those whose infants were did not report any changes in health status (asymptomatic). Statistical significance was set at P<0.05. Parametric values are presented as mean ± standard deviation and nonparametric values are presented as median (range).