Table 1.
Amino acid homology between influenza A and B viral proteins
| Protein name | Size in influenza Aa | Size in influenza Bb | Amino acid (aa) identityc |
|---|---|---|---|
| Polymerase basic 2 (PB2) |
759 aa |
770 aa |
37% |
| Polymerase basic 1 (PB1) |
757 aa |
752 aa |
58% |
| Polymerase acid (PA) |
716 aa |
726 aa |
35% |
| Hemagglutinin (HA) |
566 aa |
584 aa, 585 aad |
18% |
| Nucleoprotein (NP) |
498 aa |
560 aa |
36% |
| Neuraminidase (NA) |
469 aa |
466 aa |
20% |
| Matrix protein 1 (M1) |
252 aa |
248 aa |
27% |
| Matrix protein 2 (M2)e |
97 aa |
109 aa |
7% |
| Nonstructural protein 1 (NS1) |
219 aa, 230 aaf |
281 aa, 282 aag |
14% |
| NS2/nuclear export protein (NEP) | 121 aa | 122 aa, 123 aah | 21% |
aAmino acid sequences are from influenza A/California/07/2009(H1N1) (GenBank protein accession number: AFM72841, AFM72840, AFM72839, AFM72832, AFM72836, AFM72835, AFM72833, AFM72834, AFM72837 and AFM72838), A/Brisbane/10/2007(H3N2) (ACI26328, ACI26326, ACI26325, ACI26318, ACI26322, ACI26321, ACI26319, ACI26320, ACI26323 and ACI26324).
bAmino acid sequences are from influenza B/Wisconsin/01/2010 (B/Yamagata/16/88-lineage) (AFH57963, AFH57962, AFH57961, AFH57953, AFH57958, AFH57957, AFH57954, AFH57955, AFH57959 and AFH57960) and B/Brisbane/60/2008 (B/Victoria/2/87-like lineage) (AFH57919, AFH57918, AFH57917, AFH57909, AFH57914, AFH57913, AFH57910, AFH57911, AFH57915 and AFH57916).
cConserved amino acids among four viruses. Denominators are the proteins of A/California/07/2009(H1N1).
d584 aa for B/Wisconsin/01/2010 and 585 aa for B/Brisbane/60/2008.
eCorresponding influenza B virus protein is BM2 [19].
f219 aa for A/California/07/2009(H1N1) and 230 aa for A/Brisbane/10/2007(H3N2).
g281 aa for B/Wisconsin/01/2010 and 282 aa for B/Brisbane/60/2008.
h122 aa for B/Wisconsin/01/2010 and 123 aa for B/Brisbane/60/2008.