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. 2013 Jul 29;8(7):e70277. doi: 10.1371/journal.pone.0070277

Figure 7. The persistent PTD is unaffected by manipulations of endocannabinoid signaling.

Figure 7

A, Comparison of the averaged fEPSP/FV changes induced by 4 pulses (n = 35) or 10 pulses (n = 34) of PF stimulation at 200 Hz. B, Persistent PTD amplitude plotted against the SSE amplitude (10 pulses induction; n = 34). C, Prolongation of SSE in 1 µM JZL184. When 2 µM AM251 is added to JZL184, the remaining persistent PTD is undistinguishable from persistent PTD in AM251 alone (see Fig. 1H). D, Average persistent PTD amplitude in 2 µM AM251 (n = 13), 1 µM JZL184 and 2 µM AM251 (n = 12), 5 µM anandamide (n = 6), 10 µM capsazepine (n = 5).