Fig. 1.
Uptake of 131I-albumin (a) and 125I-leptin (b) in the brain 10 min after iv injection. The uptake of albumin was increased only in the group of EAE mice receiveing radioactively labeled tracers and unlabeled leptin on day 21 (*p<0.05 in comparison with the naïve control). The uptake of leptin was not increased in any group, but excess unlabeled leptin was able to inhibit the uptake in the EAE mice (*p<0.05; **p<0.01; ***p<0.005)