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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: J Membr Biol. 2013 Mar 24;246(10):737–744. doi: 10.1007/s00232-013-9534-y

Figure 3. The SMGA promoter acts as a cell-specific DTS in smooth muscle cells.

Figure 3

A. Cartoon of the SMGA promoter showing binding sites for various transcription factors. B. Model for cell-specific DNA nuclear transport. In smooth muscle cells, the SMGA DTS binds transcription factors that are specific to smooth muscle cells, thus forming an import competent complex. C. CV1 cells, an epithelial cell line, and primary human vascular smooth muscle cells, were cytoplasmically microinjected with plasmids carrying either the SV40 DTS or the SMGA DTS and the location of the plasmids was determined 8 hours later by in situ hybridization.