Table 5. Univariate and multivariate hazards ratios for overall survival in 248 patients with metastatic non-small cell lung cancer.

	Univariate			Multivariate
Variables	HR	95% CI	P	HR	95% CI	P
Histology
Adeno	1			1
Squamous	1.2	0.7–2.1	0.41	1.2	0.7–2.1	0.48
Large Cell	1.8	1.2–2.8	<0.01	2.2	1.4–3.4	<0.01
Mutation result
EGFR/ KRAS WT	1			1
EGFR mutation	0.4	0.2–0.7	<0.01	0.3	0.1–0.6	<0.01
KRAS mutation	1.1	0.7–1.5	0.70	1.1	0.8–1.8	0.34
No test performed	1.2	0.8–1.9	0.33	1.4	0.8–2.1	0.31
Metastasis *
Spinal bone	1.5	1.0–2.2	0.05	1.7	1.2–2.6	<0.01
Brain	0.9	0.6–1.4	0.67
Lung	1.1	0.8–1.5	0.64

HR>1 means a shorter survival.

^*denotes presence of metastasis at specific site.