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(A) The binding sites of β2AR. (B) Alprenolol forms three hydrogen bonds with Asp113, Tyr308 and Asn312. (C) BI-167107 has five hydrogen bonds with Asp113, Ser203, Ser207, Asn293 and Asn312. (D) ICI 118,551 forms two hydrogen bonds with Asp113 and Asn312.
