Table 2. Summary of genes and number of SNPs per test category.
Category | # genes | # SNPs | Highly ranked | Neuro-development | Mean p-value | SNPs with p<0.05 | SNPs with p<0.005 | ||
Obs. | Exp. | Obs. | Exp. | ||||||
1 | 73 | 1271 | Yes | Yes | 0.521 | 42 | 63.6 | 4 | 6.4 |
2 | 42 | 1525 | No | Yes | 0.480 | 103 | 76.3 | 17 | 7.6 |
3 | 52 | 929 | Yes | No | 0.488 | 63 | 46.5 | 2 | 4.6 |
1+2 | 115 | 2796 | - | Yes | 0.498 | 145 | 139.8 | 21 | 14.0 |
1+3 | 125 | 2200 | Yes | - | 0.507 | 105 | 110.0 | 6 | 11.0 |
All | 167 | 3725 | 208 | 186.3 | 23 | 18.6 |
Category 1: genes are both highly ranked and involved in neurodevelopment. Category 2: genes are exclusive to neurodevelopment. Category 3: genes are exclusively highly ranked (see details in Materials and Methods).