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. 2013 Jul 29;8(7):e67776. doi: 10.1371/journal.pone.0067776

Table 4. Four SNPs from the meta-analysis of 66 SNPs using GAIN, nonGAIN, and ISC GWAS datasets.

Gene SNP ID Chr. Position (bp) Allele Meta-analysis
p-value Beta s.e. pheterogeneity I2 pGAIN pnonGAIN pISC IHDS min p
PRKCE rs2176348 2 45798033 A/G 0.044 −0.064 0.032 0.838 0 0.470 0.599 0.057 0.004
MGMT rs552551 10 131271915 C/T 0.044 0.073 0.036 0.29 19.15 0.996 0.797 0.011 0.009
CNTN4 rs2616591 3 2614861 C/T 0.048 0.088 0.044 0.481 0 0.347 0.061 NA 0.004
NPAS2 rs2043534 2 100847317 C/T 0.062 0.064 0.035 0.635 0 0.258 0.808 0.081 0.003

Chr.: chromosome. GAIN, nonGAIN and ISC are three GWAS datasets for meta-analysis. ISHDSF min p was the smallest p-value in the gene from the IHDS dataset (this study). NA: this SNP was not analyzed in ISC due to missing genotyping data in samples.