Table 3.
Rate of | Positive predictive value | Number of | |
PCR strategy | false positives | of positive result | polymorphism tested |
Exon 10 only [1,2] | 1:1,276 | 0.999216 | 1 |
Intron 4/Exon 7 [13] | 1:4,081 | 0.999755 | 2 |
Intron 4/Exon 7/RHDψ [14] | 1:4,700 | 0.999787 | 3 |
Intron 4/Exon 7/W16X | 1:5,212 | 0.999808 | 3 |
Intron 4/Exon 7/Intron 7 | 1:6,051 | 0.999835 | 3 |
Exons 3, 4, 5, 6, 7, 9 [26] | 1:6,051 | 0.999835 | 6 |
Exons 2, 3, 4, 5, 6, 7, 9, 10 [27] | 1:6,051 | 0.999835 | 8 |
Intron 4/Exon 7/W16X/RHDψ | 1:6,267 | 0.999840 | 4 |
All Exons/RHDψ | 1:7,520 | 0.999867 | 9 |
Intron 4/Exon 7/Intron 7/W16X | 1:8,921 | 0.999888 | 4 |
Intron 4/Exon 7/Intron 7/W16X/RHDψ | 1:12,533 | 0.999920 | 5 |
* Rates were calculated based on the population frequencies of different alleles determined in the Table 2. The exact rates are population dependent and may vary according to the prevalence of alleles in the population tested.