Table 1.
Baseline characteristics among three groups (group A, B and C).
| Group A (n=129) | Group B (n=62) | Group C (n=284) | P-value A vs. B | P-value A vs. C | |
|---|---|---|---|---|---|
| Gender (male/female) | 104/25 | 42/20 | 194/90 | 0.068a | 0.013a |
| Age (years) | 68.6±8.8 | 57.7±12.3 | 69.1±7.8 | <0.001b | 0.559b |
| Hepatectomy | |||||
| Anatomical/non-anatomical | 73/56 | 30/32 | 98/186 | 0.351a | <0.001a |
| HCC stage (I/II/III/IV) | 8/74/39/8 | 5/37/19/1 | 26/164/76/18 | 0.565a | 0.724a |
| Presence of LC (yes/no) | 46/83 | 35/27 | 181/103 | 0.008a | <0.001a |
| Tumor number (single/multiple) | 84/45 | 44/18 | 186/98 | 0.511a | >0.999a |
| Maximum tumor size (cm) | 5.5±3.2 | 4.0±2.2 | 4.1±2.3 | 0.001b | <0.001b |
| Body mass index (kg/m2) | 24.1±4.0 | 22.5±3.7 | 22.8±3.6 | 0.008b | 0.002b |
| Diabetes mellitus (yes/no) | 63/66 | 7/55 | 79/204 | <0.001a | <0.001a |
| AST (IU/l) | 62.9±52.1 | 49.9±43.5 | 55.7±32.9 | 0.092b | 0.093b |
| ALT (IU/l) | 53.4±39.1 | 54.1±69.5 | 52.2±42.8 | 0.931b | 0.795b |
| ALP (IU/l) | 347.9±174.8 | 299.0±133.3 | 335.9±147.6 | 0.053b | 0.469b |
| GGT (IU/l) | 150.9±174.7 | 105.4±193.8 | 89.4±84.4 | 0.106b | <0.001b |
| Serum albumin (g/dl) | 4.00±0.49 | 4.04±0.39 | 3.75±0.49 | 0.555b | <0.001b |
| Total bilirubin (mg/dl) | 0.82±0.41 | 0.86±0.48 | 0.85±0.40 | 0.607b | 0.516b |
| Prothrombin time (%) | 91.5±15.8 | 89.7±16.9 | 87.1±13.2 | 0.472b | 0.004b |
| Platelets (×104/mm3) | 17.2±7.9 | 13.7±8.5 | 12.8±5.6 | 0.005b | <0.001b |
| AFP (ng/ml) | 1726.1±11663.8 | 2450.1±7702.4 | 2470.3±12094.2 | 0.610b | 0.558b |
| DCP (mAU/ml) | 8573.2±45695.6 | 2913.2±13229.8 | 3330.9±14306.1 | 0.196b | 0.204b |
| HCC histology | |||||
| Well/moderate/poorly/necrosis | 10/76/42/1 | 4/24/25/9 | 24/137/102/21 | <0.001a | 0.021a |
| Fibrous capsule (yes/no) | 94/35 | 53/9 | 245/39 | 0.066a | 0.001a |
| Microscopic vascular invasion (yes/no) | 55/74 | 25/37 | 92/192 | 0.876a | 0.047a |
| Microscopic surgical margin (yes/no) | 31/98 | 14/48 | 78/206 | 0.858a | 0.473a |
HCC: hepatocellular carcinoma; LC: liver cirrhosis; AST: aspartate aminotransferase; ALT: alanine aminotransferase; ALP: alkaline phosphatase; GGT: gamma glutamyl transpeptidase; AFP: alpha-fetoprotein; DCP: des-γ-carboxy prothrombin; a Fisher,s exact test; b unpaired t-test.