Table 2.
Case | Chemotherapy regimen | Transaminase baseline | Transaminase increase (grade) | WBC/Plt baseline | Neutropenia (grade) | Thrombocytopenia (grade) | G-CSF | FN | dose reduction (%) | |
---|---|---|---|---|---|---|---|---|---|---|
1 | EC | increase | 0 | normal | 4 | 3 | positive | positive | 0 | |
2 | EC | normal | 0 | normal | 0 | 0 | negative | negative | 0 | |
3 | EC | normal | 0 | normal | 4 | 1 | positive | negative | 0 | |
DTX | normal | 0 | normal | 4 | 0 | positive | positive | 75 | ||
4 | TCH | normal | 0 | normal | 4 | 1 | positive | negative | 0 | |
5 | H | normal | 0 | normal | 0 | 0 | negative | negative | 0 | |
6 | H | normal | 0 | decrease | 0 | 0 | negative | negative | 0 | |
7 | EC | increase | 1 | decrease | 4 | 3 | negative | positive | 75 | |
8 | TCH | normal | 0 | normal | 3 | 0 | negative | negative | 0 | |
9 | EC | normal | 0 | normal | 4 | 3 | positive | positive | 0 | |
wPTX | normal | 0 | decrease | 4 | 2 | positive | negative | 0 | ||
10 | G | increase | 0 | decrease | 4 | 3 | negative | negative | 75 |
WBC: white blood cell count, Plt: platelets count, G-CSF: granulocyte colony stimulating factor, FN: febrile neutropenia, EC: epirubicine + cyclophosphamide, DTX: docetaxel, TCH: docetaxel + cyclophosphamide + trastuzumab, H: trastuzumab, wPTX: weekly paclitaxel, G: gemcitabine.