Table 3.
The prevalence and adjusted ORs for MetS, its components, and insulin resistance in relation to the tertiles of uric acid and hsCRP
| Characteristics | Tertile of uric acid | Tertile of hsCRP | ||||||
|---|---|---|---|---|---|---|---|---|
| 1st N = 366 | 2nd N = 379 | 3rd N = 352 | P value | 1st N = 414 | 2nd N = 353 | 3rd N = 330 | P value | |
| <4.0 | 4.0–4.8 | >4.8 mg/dL | <0.032 | 0.032–0.071 | >0.071 mg/dL | |||
| MetS | 43 (11.7 %) | 66 (17.4 %) | 109 (31.0 %) | <0.001 | 42 (10.1 %) | 68 (19.3 %) | 108 (32.7 %) | <0.001 |
| Adjusted OR (95 % CI) | Reference | 1.45 (0.95–2.22) | 2.61 (1.74–3.93) | <0.001 | Reference | 1.80 (1.18–2.74) | 3.23 (2.15–4.85) | <0.001 |
| Components of MetS | ||||||||
| Obesity | 63 (17.2 %) | 105 (27.7 %) | 157 (44.6 %) | <0.001 | 62 (15.0 %) | 103 (29.2 %) | 160 (48.5 %) | <0.001 |
| Adjusted OR (95 % CI) | Reference | 1.63 (1.13–2.35) | 2.85 (1.98–4.10) | <0.001 | Reference | 2.15 (1.49–3.09) | 4.55 (3.17–6.54) | <0.001 |
| Raised blood pressure | 219 (59.8 %) | 253 (66.8 %) | 261 (74.1 %) | <0.001 | 249 (60.1 %) | 244 (69.1 %) | 240 (72.7 %) | 0.001 |
| Adjusted OR (95 % CI) | Reference | 1.41 (0.99–1.98) | 1.75 (1.20–2.55) | 0.012 | Reference | 1.06 (0.75–1.50) | 1.05 (0.72–1.51) | 0.945 |
| Hypertriglyceridemia | 32 (8.7 %) | 47 (12.4 %) | 81 (23.0 %) | <0.001 | 37 (8.9 %) | 49 (13.9 %) | 74 (22.4 %) | <0.001 |
| Adjusted OR (95 % CI) | Reference | 1.41 (0.87–2.28) | 2.61 (1.65–4.12) | <0.001 | Reference | 1.36 (0.86–2.17) | 2.12 (1.36–3.31) | 0.003 |
| Low HDL cholesterolemia | 64 (17.5) | 91 (24.0) | 86 (24.4) | 0.040 | 66 (15.9 %) | 78 (22.1 %) | 97 (29.4 %) | <0.001 |
| Adjusted OR (95 % CI) | Reference | 1.44 (1.00–2.08) | 1.31 (0.89–1.94) | 0.132 | Reference | 1.35 (0.93–1.95) | 1.93 (1.33–2.79) | 0.002 |
| Impaired fasting glucose | 82 (22.4 %) | 91 (24.0 %) | 113 (32.1 %) | 0.007 | 75 (18.1 %) | 97 (27.5 %) | 114 (34.5 %) | <0.001 |
| Adjusted OR (95 % CI) | Reference | 1.01 (0.71–1.44) | 1.30 (0.91–1.85) | 0.253 | Reference | 1.51 (1.06–2.15) | 1.93 (1.35–2.75) | 0.001 |
| Insulin resistancea | 36 (9.8 %) | 47 (12.4 %) | 90 (25.6 %) | <0.001 | 31 (7.5 %) | 49 (13.9 %) | 93 (28.2 %) | <0.001 |
| Adjusted OR (95 % CI) | Reference | 1.14 (0.71–1.83) | 2.28 (1.47–3.55) | <0.001 | Reference | 1.14 (0.71–1.83) | 2.28 (1.47–3.55) | <0.001 |
Study subjects were divided into three groups (tertiles) according to uric acid and hsCRP levels. Adjusted for age, current smoking status, and alcohol consumption
OR odds ratio, CI confidence interval
aInsulin resistance was defined as HOMA-IR ≥2.6