Table 1.
Sham-Sed Group | HF-Sed Group | Sham-ExT Group | HF-ExT Group | |
---|---|---|---|---|
Body weight, g | 397 ± 15 | 403 ± 23 | 365 ± 11† | 379 ± 10 |
Heart weight, g | 1.3 ± 0.1 | 2.0 ± 0.2* | 1.2 ± 0.1 | 1.9 ± 0.2* |
Infarct size, % epicardial LV | 0 | 36 ± 5* | 0 | 37 ± 4* |
LV end-diastolic pressure, mmHg | 1.3 ± 0.5 | 27.7 ± 4.5* | 1.0 ± 0.4 | 21.2 ± 4.1* |
Ejection fraction, % | 82 ± 2 | 49 ± 3* | 83 ± 2 | 50 ± 4* |
Basal mean blood pressure, mmHg | 94 ± 4 | 92 ± 3 | 90 ± 3 | 89 ± 4 |
Basal heart rate, beats/min | 346 ± 15 | 362 ± 21 | 331 ± 25 | 351 ± 24 |
Values are means ± SE; n = 10 rats/group. Sham, sham operation; Sed, sedentary; HF, heart failure; ExT, exercise training; LV, left ventricular.
P < 0.05 vs. the respective sham rats;
P < 0.05 vs. the respective Sed rats.