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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: J Pharmacokinet Pharmacodyn. 2012 Nov 27;39(6):683–710. doi: 10.1007/s10928-012-9279-8

Table 7.

PBPK model parameters

Parameter Unit
nPtorgan M  1.64 × 10−4
KdFcRn M  7.50 × 10−7
FR  0.715
R1 min−1  5.0 × 10−4
σorganV  0.95
σorganL  0.80
Tau min 127.7