Fig. 2.

Cardiac substrate oxidation in mTOR KO hearts measured in ex vivo working hearts. A: cardiac output, cardiac power, and aortic pressure measured in working hearts. n = 5–8. B: palmitate oxidation, O₂ consumption, and cardiac efficiency measured in working hearts. n = 5–8. C: glucose oxidation measured in working hearts. n = 5–7. D: free glucose, glucose-6-phosphate, lactic acid, 2-phosphoglycerate, and 3-phosphoglycerate in control and mTOR KO hearts measured by gas chromatography-mass spectrometry. n = 6–8. AU, arbitrary units. *P < 0.05; **P < 0.01.