Table 1.
Baseline characteristics of the study population
| Characteristic | Total population, N = 123 |
|---|---|
| Age (y) | 70 (58–82) |
| Male sex (%) | 70 (57) |
| Comorbid disease | |
| Coronary artery disease (%) | 46 (37) |
| Congestive heart failure (%) | 36 (29) |
| Chronic obstructive pulmonary disease (%) | 27 (21) |
| Diabetes (%) | 43 (35) |
| Hypertension (%) | 63 (51) |
| Kidney disease (%) | 33 (27) |
| Liver disease (%) | 9 (7.3) |
| Initial vitals | |
| Temperature (F) | 98.7 (97.4–100.3) |
| Heart rate (beats per minute) | 100 (82–118) |
| Respiratory rate (beats per minute) | 20 (16–28) |
| Mean arterial pressure (mm Hg) | 70 (61–87) |
| Laboratory data | |
| White blood cell (×103/μL) | 12.6 (7.9–19.8) |
| Hematocrit (%) | 34.3 (30–39) |
| Platelets (×103/μL) | 248 (167–338) |
| Glucose (mg/dL) | 131 (100–171) |
| INR | 1.4 (1.2–2.3) |
| ALT (U/L) | 28 (17–63) |
| AST (U/L) | 35 (24–94) |
| Creatinine | 1.6 (1.1–2.7) |
| Lactic acid (mmol/L) | 2.7 (1.9–4.1) |
| Infection source | |
| Lung (%) | 52 (42) |
| Urine (%) | 27 (22) |
| Intraabdominal (%) | 15 (12) |
| Other/unknown (%) | 29 (24) |
| Blood culture positive | 32 (26) |
| Acute liver injury (%) | 22 (18) |
| Acute renal injury (%) | 59 (48) |
| Intubated | 58 (46) |
| Vasopressor time (h) | 61 (26–101) |
| APACHE II | 20 (13–26) |
| SOFA | 7 (5–10) |
| 28-day mortality (%) | 36 (29) |
Medians and IQR are reported for continuous variables.
Categorical variables are reported as frequencies with percentages.