Elucidation of Novel Structural Scaffold in Rohu TLR2 and Its Binding Site Analysis with Peptidoglycan, Lipoteichoic Acid and Zymosan Ligands, and Downstream MyD88 Adaptor Protein

. 2013 Jul 15;2013:185282. doi: 10.1155/2013/185282

(b) Stereochemical quality of homology models by ProQ, ModFOLD, and MetaMQAP server

	TLR2-ECD	TLR2-TIR	MyD88-TIR
ProQ (LG/MX)	7.062/0.432	6.401/0.772	7.067/0.847
ModFOLD (Q/P)	0.6326/0.0065	0.7473/0.00038	0.5787/0.0022
MetaMQAP (GDT/RMSD)	68.93/2.137	78.767/1.523	72.628/2.319

*ProQ-LG: >1.5 fairly good; >2.5 very good; >4 extremely good. ProQ-MX: >0.1 fairly good; >0.5 very good; >0.8 extremely good. ModFOLD-Q: >0.5 medium confidence; >0.75 high confidence. ModFOLD-P: <0.05 medium confidence; <0.01 high confidence. MetaMQAP-GDT/RMSD: an ideal model has a GDT score over 59 and an RMSD around 2.0 Å.