Figure 1. Backbone resonance assignment of the minor slow exchange conformation in the C22V variant of human FKBP12.

Strips from the HN(CO)CACB (left) and HNCACB (right) datasets at the ¹⁵N frequencies for the amide resonances of the minor slow exchange conformation are illustrated for the sequence from Thr⁸⁵ to His⁸⁷. The C^α resonances are phased to yield positive (black) cross-peaks, whereas the C^β cross-peaks are negative (red).