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. Author manuscript; available in PMC: 2013 Jul 30.
Published in final edited form as: J Proteome Res. 2008 Feb 1;7(3):1109–1117. doi: 10.1021/pr700702r

Figure 5.

Figure 5

(A) Probing conformational changes of glycan isomers by IMS-IMS–MS. Precursor and mobility selected drift time distributions for [S2H5N4 + 3Na]3+ (m/z = 946.7) at three different selection times (shown by dashed lines). The drift time distributions for mobility selected precursors are obtained after gentle activation of ions at IA2. (B) Probing conformational changes of isomers by IMS-IMS–MS (continued). Precursor and mobility selected drift time distributions for [S1H5N4 + 3Na]3+ (m/z = 826.0) at three different selection times (shown by dashed lines). The drift time distributions for mobility selected precursors are obtained after gentle activation of ions at IA2. Selections made for low mobility precursors are dominated by similar features with an identical distribution after ion activation indicating presence of one isomer. High-mobility region is dominated by features that do not show similar distribution upon ion activation indicating presence of another isomer.