Table 1. B.
Conditions | RR/PR | ||||
Girk4−/−NaCl | WTAtrop | Girk4−/−Atrop | WTProp | Girk4−/−Prop | |
WTNaCl | NS/NS | <0.05/NS | <0.01/<0.05 | <0.01/NS | <0.001/NS |
Girk4−/−NaCl | NS/NS | <0.05/NS | <0.001/NS | <0.001/<0.01 | |
WTAtrop | NS/NS | <0.001/<0.01 | <0.001/<0.001 | ||
Girk4−/−Atrop | <0.001/<0.001 | <0.001/<0.001 | |||
WTProp | NS/NS |
Atrop, atropine; Prop, propranolol. ECG interval values in WT and Girk4−/− mice under control conditions (intraperitoneal injection of NaCl) or after systemic administration of 0.5 mg/kg atropine or 5 mg/kg propranolol are shown.