Figure 1.
Modeling and electrostatics of pH1N1 HA mutants. The structures and electrostatic potentials of pH1N1 HAs with G158E or K133N mutants were modeled. Shown are pH1N1-WT (A) and computationally modeled pH1N1 HAs with G158E (B) or K133N (C) mutations. Sialic acid is shown as a stick structure. Surface coloring indicates electrostatic potential in units of kT/e where k is Boltzmann’s constant, T is temperature, and e is the elementary charge.